Our Awards and Programs

To achieve our vision of a world without ALS, we support nearly every stage of research, from identifying ALS-linked genes and biomarkers to discovering and developing new treatments to optimizing current treatment approaches and quality of life. We also encourage young scientists to pursue careers in ALS and build research and clinical trial infrastructure to cultivate a robust pipeline of innovative ideas that can lead to better ALS treatments and ultimately a cure. 

Research Pipeline

Research Grants


Lawrence and Isabel Barnett Drug Development Program

This grant program supports preclinical drug discovery and development of new or repurposed treatments for ALS.
Clinician and patient

Clinical Trial Awards

This program supports early-stage interventional clinical trials of novel or repositioned therapeutics for ALS.
Patient and doctor

Trial Capacity Awards

These grants support efforts to increase participation and diversity in ALS clinical trials as well as efforts to improve the speed and efficiency of these trials.
Clinician and patient

Prevention Grants

This program supports efforts to prevent or delay the harms of ALS, with the goal of impacting clinical care within the next 5–7 years.
Researcher taking notes

Seed Grants

These awards provide 1 year of support so researchers can gather the data needed to secure follow-on funding and partnerships to advance potentially impactful ALS research.

Partnership Grants

These awards support grant-making efforts at other nonprofits that have the potential to ultimately transform the experience of ALS.

Sheila Essey Award for ALS Research

This annual award recognizes significant contributions in the search for the causes, prevention and a cure for ALS.



Milton Safenowitz Postdoctoral Fellowship Program

This program supports the development of early-career scientists by funding junior postdoctoral fellows doing research of high scientific merit and relevance to ALS.
Young researcher

Clinical Fellowship Programs

These awards, established in partnership with the American Academy of Neurology and American Brain Foundation, give young investigators the experience they need to establish their own ALS research laboratories and continue moving their innovative ideas toward the clinic.
Funding Opportunities for Researchers
To help make ALS a livable disease until we can cure it, we annually review and refine our research portfolio with input from our Research Committee. Click below to explore current and past requests for applications.
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