Research

We are the largest private funder of ALS Research worldwide, and our efforts have led to some of the most promising and significant advances in ALS research. 

We have the premier ALS research program in the world. 

Everything we do supports our mission of finding treatments and a cure for ALS, which is why it is so critical to fund outstanding ALS research. Thanks to the donations raised during the ALS Ice Bucket Challenge, we are now spending three times more than on ALS Research than before summer 2014.

researcher conversing with patient
AMX0035 Results

AMX0035 Results: Implications for People with ALS

Dr. Neil Thakur and Dr. Kuldip Dave from the ALS Association discuss the implications of the CENTAUR trial for the ALS community.

Read more about AMX0035

FAQs: 2020 Research & COVID-19
The ongoing COVID-19 situation is impacting many industries and efforts worldwide. Below are some frequently asked questions about how The ALS Association will be responding in terms of its 2020 research goals.
Lab technician testing samples

Partnerships & Initiatives

From harnessing innovative ideas, to translating concepts to therapies, to advancing treatments to people living with ALS – The ALS Association’s collaborative and global approach to funding research continues to lead to significant discoveries by top ALS scientists around the world.  

Collaboration is the cornerstone of our research program. We partner with academia, industry, government, and other nonprofit organizations. We lead by spurring long-lasting collaborations among researchers across all sectors, leading to globally shared data, protocols, and research samples to accelerate research progress. 

Learn More

Our progress in accelerating the pace of discovery

Due to the huge funding boost from generous donors during the ALS Ice Bucket Challenge, so far we have committed more than $111 million to research alone, not including investments in the other core pillars of The ALS Association. This commitment is focused on specific projects and large global initiatives to help drive progress toward finding treatments and a cure for ALS.  

  • 3 potential new ALS antisense drugs
  • Key advances in wearable sensor and brain computer interface technology
  • New treatment approaches in clinical trials
  • Research Discoveries
Dr. Don Cleveland
With The ALS Association’s ongoing support, my work in antisense technology, which was once thought of as innovative and risky, has led to clinical trials that could help people with ALS and other neurodegenerative diseases."
Don Cleveland, Ph.D.
University of California at San Diego
Elected Member, National Academy of Sciences
Antonia Dominguez, Ph.D.
I was extremely honored to receive a fellowship grant from The ALS Association to further my work in studying ALS because I know that so many people apply. It has already helped advance my work on tuning the levels of the C9orf72 gene, the most common genetic mutation in ALS."
Antonia Dominguez, Ph.D.
Milton Safenowitz Postdoctoral Fellow