We are the largest philanthropic funder of ALS research in the world, supporting projects around the globe with the highest potential impact for people living with ALS and their caregivers. Since the Ice Bucket Challenge in 2014, we have committed over $154 million to support more than 550 projects in the U.S. and 18 other countries, with the goal of making ALS a livable disease until we can cure it.

Our Priorities

Accelerate New Treatments & Technologies

People living with ALS urgently need new ways to treat the disease, manage symptoms, and maintain their independence. To accelerate the availability of new treatments and technologies, we not only support discovery and development efforts but also build critical research infrastructure and help improve the accessibility and efficiency of clinical trials.

doctor evaluating person living with ALS

Optimize Current Treatments & Care

A critical component of making ALS livable is ensuring that people with ALS are getting the best possible care. We support research looking to optimize the use of telehealth, wearable sensors, and genetic testing and counseling, as well as better understand the preferences, needs, and experiences of people living with ALS and their caregivers to stimulate change.

Reduce the Harms of ALS

Supported by our funding, researchers around the world are looking to better understand the underlying factors that cause ALS, not just to find new ways of treating the disease but also ways to prevent it from ever occurring. We also support research into biomarkers and technologies that can be leveraged to detect and diagnose ALS sooner.

See What We Fund

Driving Discovery

Cutting-edge research is transforming the experience of being diagnosed and living with ALS. Thanks to the Ice Bucket Challenge and the generosity of our donors, here’s just some of the progress we’ve made so far:

The first genetically targeted therapy to treat ALS was approved by the Food and Drug Administration.

More than 40 genes have been linked to ALS risk and development.

Stem cells generated from individuals' skin cells are laying the foundation for a new era of precision medicine for ALS.

New brain-computer interface technology can translate brain signals into speech with up to 97% accuracy.

See the impact of our research programs

Clinical Research Week: Your Path to Advancing ALS Research

Study Demonstrates Sustained Stabilization and Functional Recovery in SOD1-ALS Patients Treated with Qalsody (Tofersen)

New Qalsody Results Bring Hope for Recovery of Lost Function and More Time

Go Behind the Headlines 

Stories about ALS research advancements are filled with information about different genes, proteins and other scientific concepts. Get a better understanding of what it all means in a way that’s easy to understand. 

Explore ALS research topics

With Your Help, We Can Make ALS Livable.

Your gift will support research that can transform the lives of people with ALS and their families—and help find a cure.

Donate Today

ALS Assocation

ALS Research