thinkALS™ for Faster Diagnosis

On average, it takes 10-15 months from the time a person first notices symptoms to receiving an ALS diagnosis. During this time, they are often subject to redundant and painful diagnostic testing and even erroneous diagnoses that result in unnecessary treatments, such as spine surgeries, carpal tunnel releases and immunotherapies.

Diagnostic delays not only cause significant anxiety and stress for individuals and families, but also prevent people with ALS from:​

  • Accessing multidisciplinary care​
  • Receiving disease-modifying medications and life-sustaining treatments (e.g., noninvasive ventilation, feeding tubes) 
  • Enrolling in clinical trials​
  • Pursuing disability benefits​
People with ALS cannot wait, so we are encouraging all health care providers to “think ALS” from the very beginning.
Doctor and patient


thinkALS is an easy-to-use and powerful tool that can help reduce the time it takes to diagnose the disease and refer people to multidisciplinary ALS clinics.* The tool provides primary care doctors, neurologists, allied health professionals and other non-ALS specialists with a comprehensive list of key clinical features of the disease that may lead them to suspect an ALS diagnosis.


thinkALS was developed by a dedicated group of ALS clinicians and physician scientists and reviewed in depth by members of the Time to Diagnosis Working Group, which also included people with ALS, caregivers, pharmaceutical industry representatives and ALS Association leaders.

*This tool cannot be substituted as a diagnostic instrument but used only as a diagnostic guide. 

Referrals to Multidisciplinary ALS Clinics

Our goal is for consultations at ALS clinics to happen within two weeks of referral. Most ALS centers in the United States can accommodate urgent ALS referrals within this timeframe, but the correct referral language is needed. Please state clearly in your referral “CLINICAL SUSPICION FOR ALS.”


Click here for additional ALS specialist sites, including medical institutions in Japan, Israel, Mexico, Canada, Australia, Turkey, India and Italy.

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