Hello- my 67 year old sister was diagnosed with progressive motor neuron disease and could no longer walk, turn pages in a book, lift a glass, etc. She was started on cholestyramine 4 months ago (for unrelated reason), and is slowly regaining the use of her hands and arms. She is also able to move her toes again. I read the recent results of a study suggesting that altered cholesterol metabolism may have something to do with ALS (not sure if causal or effect), and wondered if anyone has ever seen reversal of function in ALS. Thank you.